Caim is a GUI application can perform information-theoretic analyses of videographic data.
Inform is a framework of tools for information-theoretic analysis of complex systems.
Inform is backed by a C library.
PyInform is a Python wrapper for Inform.
Neet is an effort to develop a usable package for analyzing the structure of dynamical Boolean networks.
Ginger is a C library to fill some gaps in the C-standard library.